Why Contraceptive Innovation?

Despite the availability of various contraceptive methods, more than 200 million women in developing countries want to avoid or delay pregnancy yet are not using an effective family planning method. For some of these women, access to contraception is limited. For others, currently available methods do not meet their needs or preferences or are unaffordable. Innovative solutions are needed in the areas of product development, registration, pricing, and introduction to address these barriers.

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Visit our resource library for additional information about the need for contraceptive innovation.

Resources

A one-stop shop for resources related to contraceptive research and development

The CTI Exchange offers resources about contraceptive research and development, including information about products currently in development, preclinical and clinical research, and opportunities for future investment. This easily searchable resource library also includes information about regulatory requirements, quality assurance standards, intellectual property, and product introduction strategies, as well as tools for advocacy.

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Updates

Latest news, events, resources, and thought pieces from the Exchange's blog

blog

FDA approvals for Annovera and Natural Cycles app
On August 10, 2018, the U.S. Food and Drug Administration made two major announcements related to contraception. The FDA permitted marketing of Natural Cycles and it approved AnnoveraTM.
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blog

Newly Published: Can WIN 18,446 function as a nonhormonal fema...
Vitamin A deficient women produce less retinoic acid, and this deficiency reduces their fertility. Meanwhile, the compound WIN 18,446 inhibits retinoic acid production. WIN 18,446 has a...
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blog

A Summer in Contraceptive Development
This summer, we got to work in CTI as undergraduate interns. We knew we were going to be working in contraceptive research and development (R&D), but there were far fewer lab coats and chemi...
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blog

New Summer Twitter Campaign: #NextGenContraception
The CTI Exchange’s summer social media campaign aims to highlight the importance of new contraceptive research and development to meet the needs and preferences of women and men globally. ...
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blog

Report on the International Family Planning Landscape
The Center for Global Development (CGD) and Kaiser Family Foundation (KFF) held an international family planning leadership retreat to discuss the current landscape of the field.
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blog

Newly Published Results of a Phase I/II Trial for LNG-only Patche...
A recently published article reports on a phase I/II pharmacokinetic and pharmacodynamic clinical trial of two levonorgestrel (LNG)-only contraceptive patches.
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blog

Published Review on Responses to Contraceptive-Induced Menstrual ...
A recently published review in Reproductive Health summarizes research on women’s responses to contraceptive-induced menstrual bleeding changes (CIMBCs).
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blog

Vaginal Ring Dose-Finding Results Published
Results from a dose-finding study on a novel vaginal ring utilizing 17β-estradiol rather than ethinyl estradiol were published in the May issue of Contraception.
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event

Upcoming Webinar Series: “Mind the Gap”
The Reproductive Health Supplies Coalition is hosting a webinar series, titled “Mind the Gap”, on their latest Global Contraceptive Commodity Gap Analysis (CGA 2018).
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blog

NIH Announces Funding for Novel Contraceptive Methods
The National Institutes of Health has released a new funding solicitation to support the development of novel nonsteroidal contraceptive methods.
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commentary

Contraceptive Technology Innovation: A Wise Investment
As long as women and men find current family planning methods unacceptable, unaffordable, or inaccessible, there will be a need to invest in contraceptive technology innovation.
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commentary

Contraceptive Technology Innovation: It’s Everyone’s Business
Everyone must be engaged to move the science of contraceptive technology innovation forward – to bring it out of the laboratories and get it to the people who need it on the ground.
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Featured Resources

Other key resources related to contraceptive research and development

Calliope, the Contraceptive Pipeline Database, includes information on potential contraceptive targets and leads, products in pre-clinical and clinical development, and a selection of novel and long-acting products with limited market availability.
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CAPRI, the Contraceptive Active Pharmaceutical Ingredient Database, lists biological and chemical properties for 27 active pharmaceutical ingredients found in contraceptives, along with data on their pharmacology, toxicology, impurities, metabolites, and use in marketed products.
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Contraceptive Drug Interactions is a database that catalogues potential interactions between contraceptive drugs and drugs from other therapeutic classes. Changes in drug pharmacokinetics, effectiveness, and adverse effects are provided.

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